GABA RECEPTORS AND PAIN REGULATION
نویسندگان
چکیده
منابع مشابه
GABA signaling regulation by GLP-1 receptor agonists and GABA-A receptors modulator
Babateen, O. M. 2016. GABA signaling regulation by GLP-1 receptor agonists and GABAA receptors modulator. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1209. 51 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9548-0. GABA (γ-aminobutyric acid) is the main neuroinhibitory transmitter in mammalian brains. It binds to GABA-A and GABA-B receptors...
متن کاملGABA Receptors
Ian Martin is Professor of Pharmacology in the School of Life and Health Sciences at the University of Aston, Birmingham B4 7ET, UK. Susan Dunn is a Senior Lecturer in the Department of Pharmacology at the University of Bristol, University Walk, Bristol BS8 1TD, UK. They have common interests in GABAergic transmission in the central nervous system and their research is focused on the structure-...
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Activation of protein kinase C (PKC) by phorbol 12-myristate 13-acetate induced a continuous decrease in the gamma-aminobutyric acid (GABA)-activated current amplitude from recombinant GABA receptors (formed by rho1 or alphabetagamma subunits) expressed in Xenopus oocytes. This decline was due to internalization of receptors from the plasma membrane as confirmed by a decrease in surface fluores...
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From an historical standpoint, the development of our understanding of basic mechanisms of the actions of gamma aminobutyric acid (GABA) and benzodiazepines began on separate paths. Classical pharmacology revealed similarity between the actions of GABA and benzodiazepines in the central nervous system. Furthermore, pharmacological experiments with selective agonists and antagonists indicated th...
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Chronic stressors produce changes in hippocampal neurochemistry, neuronal morphology, and hippocampal-dependent learning and memory processes. In rats, stress-induced changes in CA3 apical dendritic structure are mediated by corticosterone (CORT) acting, in part, on excitatory amino acid neurotransmission. CORT also alters GABA-mediated inhibitory neurotransmission, so the GABA(A) receptor syst...
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ژورنال
عنوان ژورنال: Istituto Lombardo - Accademia di Scienze e Lettere - Rendiconti di Scienze
سال: 2012
ISSN: 2384-986X,1974-6989
DOI: 10.4081/scie.2012.137